Three-dimensional mitochondrial arrangement in ventricular myocytes: from chaos to order

Posted on July 5, 2006September 18, 2014 by Birkedal R, Shiels HA, Vendelin M

Birkedal R, Shiels HA, Vendelin M Am. J. Physiol., Cell Physiol. 2006 Dec;291(6):C1148-58 PMID: 16822946 Abstract We have developed a novel method to quantitatively analyze mitochondrial positioning in three dimensions. Using this method, we compared the relative positioning of mitochondria in adult rat and rainbow trout (Oncorhynchus mykiss) ventricular myocytes. Energetic data suggest that trout, in contrast to the rat, have two subpopulations of mitochondria in their cardiomyocytes. T...

Mitochondrial regular arrangement in muscle cells: a “crystal-like” pattern

Posted on October 20, 2004September 18, 2014 by Vendelin M, Béraud N, Guerrero K, Andrienko T, Kuznetsov AV, Olivares J, Kay L, Saks VA

Vendelin M, Béraud N, Guerrero K, Andrienko T, Kuznetsov AV, Olivares J, Kay L, Saks VA Am. J. Physiol., Cell Physiol. 2005 Mar;288(3):C757-67 PMID: 15496480 Abstract The aim of this work was to characterize quantitatively the arrangement of mitochondria in heart and skeletal muscles. We studied confocal images of mitochondria in nonfixed cardiomyocytes and fibers from soleus and white gastrocnemius muscles of adult rats. The arrangement of intermyofibrillar mitochondria was analyzed...