
Laasmaa M, Vendelin M, Peterson P
J Microsc 2011 Aug;243(2):124-40
PMID: 21323670
Abstract
Although confocal microscopes have considerably smaller contribution of out-of-focus light than widefield microscopes, the confocal images can still be enhanced mathematically if the optical and data acquisition effects are accounted for. For that, several deconvolution algorithms have been proposed. As a practical solution, maximum-likelihood algorithms with regularization have been used. Howe...
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