Martin Laasmaa

I defended my PhD in December of 2016 in the field of Engineering Physics at the Tallinn University of Technology. Currently, I am working as a researcher at the Laboratory of Systems Biology. My main research interests are calcium handling during excitation-contraction coupling and molecule movements in a single cardiomyocytes.

Publications

Lu, P., Veletić, M., Laasmaa, M., Vendelin, M., Louch, W. E., Halvorsen, P. S., … Balasingham, I. (2019). Multi-nodal nano-actuator pacemaker for energy-efficient stimulation of cardiomyocytes. Nano Communication Networks, 22, 100270. https://doi.org/10.1016/j.nancom.2019.100270
Laasmaa, M., Lu, P., Veletić, M., Louch, W. E., Bergsland, J., Balasingham, I., & Vendelin, M. (2019). Energy-efficiency of Cardiomyocyte Stimulation with Rectangular Pulses. Scientific Reports, 9(1), 1–9. https://doi.org/10.1038/s41598-019-49791-w
Karro, N., Laasmaa, M., Vendelin, M., & Birkedal, R. (2019). Respiration of permeabilized cardiomyocytes from mice: no sex differences, but substrate-dependent changes in the apparent ADP-affinity. Scientific Reports, 9(1), 1–11. https://doi.org/10.1038/s41598-019-48964-x
Laasmaa, M., Karro, N., Birkedal, R., & Vendelin, M. (2019). IOCBIO Sparks detection and analysis software. PeerJ, 7, e6652. https://doi.org/10.7717/peerj.6652
Laasmaa, M., Birkedal, R., & Vendelin, M. (2016). Revealing calcium fluxes by analyzing inhibition dynamics in action potential clamp. Journal of Molecular and Cellular Cardiology, 100, 93–108. https://doi.org/10.1016/j.yjmcc.2016.08.015
Karro, N., Sepp, M., Jugai, S., Laasmaa, M., Vendelin, M., & Birkedal, R. (2016). Metabolic compartmentation in rainbow trout cardiomyocytes: coupling of hexokinase but not creatine kinase to mitochondrial respiration. Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology. https://doi.org/10.1007/s00360-016-1025-x
Simson, P., Jepihhina, N., Laasmaa, M., Peterson, P., Birkedal, R., & Vendelin, M. (2016). Restricted ADP movement in cardiomyocytes: Cytosolic diffusion obstacles are complemented with a small number of open mitochondrial voltage-dependent anion channels. Journal of Molecular and Cellular Cardiology, 97, 197–203. https://doi.org/10.1016/j.yjmcc.2016.04.012
Birkedal, R., Laasmaa, M., & Vendelin, M. (2014). The location of energetic compartments affects energetic communication in cardiomyocytes. Frontiers in Physiology, 5, 376. https://doi.org/10.3389/fphys.2014.00376
Illaste, A., Laasmaa, M., Peterson, P., & Vendelin, M. (2012). Analysis of Molecular Movement Reveals Latticelike Obstructions to Diffusion in Heart Muscle Cells. Biophysical Journal, 102(4), 739–748. https://doi.org/10.1016/j.bpj.2012.01.012
Laasmaa, M., Vendelin, M., & Peterson, P. (2011). Application of regularized Richardson-Lucy algorithm for deconvolution of confocal microscopy images. Journal of Microscopy, 243(2), 124–140. https://doi.org/10.1111/j.1365-2818.2011.03486.x

Contact

Email: martin@sysbio.ioc.ee
Address:
Laboratory of Systems Biology
Department of Cybernetics
School of Science
Tallinn University of Technology
Akadeemia tee 21B
12618 Tallinn
Estonia
Phone: (+372) 620 4406


Other Resources

Estonian Science Portal
ResearchGate