
Sokolova N, Pan S, Provazza S, Beutner G, Vendelin M, Birkedal R, Sheu SS
PLoS ONE 2013;8(12):e83214
PMID: 24349464
Abstract
ADP is not only a key substrate for ATP generation, but also a potent inhibitor of mitochondrial permeability transition pore (mPTP). In this study, we assessed how oxidative stress affects the potency of ADP as an mPTP inhibitor and whether its reduction of reactive oxygen species (ROS) production might be involved. We determined quantitatively the effects of ...
Read More