
Kalda M, Vendelin M
Sci Rep 2020 Mar;10(1):5530
PMID: 32218497
Full text: https://doi.org/10.1038/s41598-020-62452-7
Abstract
Model simulations (top) and the scheme showing cooperativity modes
Strong interactions between cross-bridges (XB) and regulatory units (RU) lead to a steep response of cardiac muscle to an increase in intracellular calcium. We developed a model to quantitatively assess the influence of different types of interactions within the sarcomere on the prope...
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