Extraction of quantitative parameters from live- and fixed-cell fluorescence data.
What we can do:
- Confocal, TIRF, and epifluorescence microscopy
- Superresolution fluorescence microscopy (dSTORM, DNA-PAINT)
- Raster image correlation spectroscopy and diffusion analysis
- Fluorescence Correlation Spectroscopy
- Three-dimensional analysis of subcellular organization in live cells
- Image deconvolution and resolution enhancement
- Open-source, reproducible analysis pipelines
Typical problems this enables:
- Detection of early structural dysfunction
- Understanding how cellular architecture constrains function
- Identification of structural biomarkers linked to disease progression