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Welcome to the Laboratory of Systems Biology
Example of the response of permeabilized cardiomyocytes to changes in solution. From the analysis of autofluorescence changes (NADH and flavoproteins, Fp), we estimated the intracellular diffusion restrictions. See Jepihhina et al, Biophys J 2011 for details
Welcome to the site of the Laboratory of Systems Biology. The Laboratory of Systems Biology is a part of the Center for Nonlinear Studies in Institute Of Cybernetics, Tallinn University of Technology.
Aim
The main aim of the laboratory is to study regulation of intracellular processes and understand functional influences of intracellular interactions. For this, a mixture of experimental and theoretical approaches are used.Specific scientific interests, projects
- Intracellular compartmentation and diffusion restrictions, influence on bioenergetics
- How the fine structure of mitochondrion is influencing the dynamics of oxidative phosphorylation?
- Regulation of energy transfer in different types of cells
- Metabolic stability of heart muscle cells
- Interaction between mechanics and energetics of the heart
Support
The research in laboratory is financed byContact
Head: Marko Vendelin
Laboratory of Systems Biology
Institute of Cybernetics
Tallinn University of Technology
Akadeemia 21
12618 Tallinn
Estonia
Fax: +372 620 4151
Phone: +372 620 4169
http://sysbio.ioc.ee
Ardo Illaste's thesis defense