Marko Vendelin

I am the head of the Laboratory of Systems Biology and Professor of Biophysics at the Department of Cybernetics. I defended my PhD in 2001 at the Institute of Cybernetics at Tallinn University of Technology. After continuing my research at the Institute of Cybernetics in 2002, I was a postdoctoral fellow at Université J. Fourier (2003-2004, Laboratory of Fundamental and Applied Bioenergetics, INSERM E0221) and Université Paris-Sud (2005, Faculté de Pharmacie, INSERM U446). After my postdoctoral studies, I returned to the Institute of Cybernetics and, with the help of a Wellcome Trust International Senior Research Fellowship, started the Laboratory of Systems Biology in 2007.

Research Interests

My general research interests are linked to the physiology of the heart. I am interested in the regulation of bioenergetics and its links to mechanics and electrophysiology. As part of my studies of the regulation of intracellular processes in the heart, I study molecular movements and how intracellular communication is influenced by the local environment and different diffusion obstacles in heart muscle cells. For specific aims and interests, see the general homepage of the Laboratory of Systems Biology.

Contact

e-mail: markov@sysbio.ioc.ee

Address:

Laboratory of Systems Biology
Department of Cybernetics
School of Science
Tallinn University of Technology
Akadeemia 15,
12618 Tallinn
ESTONIA

phone: +372 5399 4915

Publications

All publications: click here

Online supplements and corrections to papers: click here

Latest publications

Karimi, H., Gustavson, O., Česnokova, I., Branovets, J., Birkedal, R., Laasmaa, M., & Vendelin, M. (2026). A Unified Platform for FCS and RICS Analysis with Advanced Statistical Inference. ACS Omega, 11(12), 19201–19219. https://doi.org/10.1021/acsomega.5c12269
Branovets, J., Laasmaa, M., Stolova, J., Shen, X., Rätsepso, T., Bernasconi, R., Soodla, K., Balodis, M. J., Grahv, C., Hendrikson, E., Louch, W. E., Birkedal, R., & Vendelin, M. (2025). Lifelong creatine deficiency leads to augmented sarcoplasmic reticulum calcium release but not heart failure. American Journal of Physiology-Heart and Circulatory Physiology, 329(2), H471–H489. https://doi.org/10.1152/ajpheart.00106.2025
Karimi, H., Laasmaa, M., Pihlak, M., & Vendelin, M. (2025). Statistical analysis of fluorescence intensity transients with Bayesian methods. Science Advances, 11(16), eads4609. https://doi.org/10.1126/sciadv.ads4609