News

A Unified Platform for FCS and RICS Analysis with Advanced Statistical Inference

Hamed Karimi, Otto Gustavson, Irina Česnokova, Jelena Branovets, Rikke Birkedal, Martin Laasmaa, Marko Vendelin

ACS Omega, 2026 Mar 31; 11(12): 19201-19219.

• PMID: 41939380
• DOI: 10.1021/acsomega.5c12269

S

Lifelong creatine deficiency leads to augmented sarcoplasmic reticulum calcium release but not heart failure

Jelena Branovets, Martin Laasmaa, Jekaterina Stolova, Xin Shen, Triinu Rätsepso, Romain Bernasconi, Kärol Soodla, Mihkel Jaan Balodis, Cärolin Grahv, Eliise Hendrikson, William Edward Louch...

Statistical analysis of fluorescence intensity transients with Bayesian methods.

Hamed Karimi, Martin Laasmaa, Margus Pihlak, Marko Vendelin

Sci Adv, 2025 Apr 18; 11(16): eads4609.

• PMID: 40249821
• DOI: 10.1126/sciadv.ads4609

Abstract

Molecular movement and interactions at the singl...

Higher AMPK activation in mouse oxidative compared with glycolytic muscle does not correlate with LKB1 or CaMKKβ expression

Romain Bernasconi, Kärol Soodla, Alex Sirp, Kairit Zovo, Maria Kuhtinskaja, Tiit Lukk, Marko Vendelin, Rikke Birkedal

Am J Physiol Endocrinol Metab, 2025 Jan 01; 328(1): E...

Compartmentalization in cardiomyocytes modulates creatine kinase and adenylate kinase activities

Rikke Birkedal, Jelena Branovets, Marko Vendelin

FEBS Lett, 2024 Nov; 598(21): 2623-2640.

• PMID: 39112921
• DOI: 10.1002/1873-3468.14994

Significance

Heart muscle cells contain densely pa...

Simple Analysis of Gel Images With IOCBIO Gel Software

Lucia Jaska, Rikke Birkedal, Martin Laasmaa, Marko Vendelin

Bio Protoc, 2024 Aug 20; 14(16): e5053.

• PMID: 39210956
• DOI: 10.21769/BioProtoc.5053

Significance

Gel images are widely used in biology, but results can be hard to rep...

Simple analysis of gel images with IOCBIO Gel

Jaak Kütt, Georg Margus, Lauri Kask, Triinu Rätsepso, Kärol Soodla, Romain Bernasconi, Rikke Birkedal, Priit Järv, Martin Laasmaa, Marko Vendelin

BMC Biol, 2023 Oct 20; 21(1): 225.

• PMID: 37864184
• DOI: 10.1186/s12915-023-01734-8

Significa

Cardiomyocytes from female compared to male mice have larger ryanodine receptor clusters and higher calcium spark frequency

Martin Laasmaa, Jelena Branovets, Jekaterina Stolova, Xin Shen, Triinu Rätsepso, Mihkel Jaan Balodis, Cärolin Grahv, Eliise Hendrikson, William Edward Louch, Rikke Birkedal,...

Ontogeny of cardiomyocytes: ultrastructure optimization to meet the demand for tight communication in excitation-contraction coupling and energy transfer

Rikke Birkedal, Martin Laasmaa, Jelena Branovets, Marko Vendelin

Philos Trans R Soc Lond B Biol Sci, 2022 Nov 21; 377(1864): 20210321.

• PM...

Cardiac expression and location of hexokinase changes in a mouse model of pure creatine deficiency

Jelena Branovets, Niina Karro, Karina Barsunova, Martin Laasmaa, Craig A Lygate, Marko Vendelin, Rikke Birkedal

Am J Physiol Heart Circ Physiol, 2021 Feb 01; 320(2): H613-H629.

• PMID: 33337958...